Exercise can help combat fatigue; a simple daily walk with a friend can help. Eating a healthy diet helps you deal with side effects and fight infections. If this were to happen, the only fix is an invasive surgery. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. I was diagnosed with grade 3 breast cancer in may. I had infusions every 21 days. Best wishes for continued good health. Best wishes Jules xxx. OR. Other effects for me are tingling in feet, skin peeling off, mostly in feet, toe nails highly sensitive. The pain is horrendous and for me it moves from anywhere to anywhere. Good luck with your next cycle and hopefully you too will benefit from the treatment. I am sorry to read that the chemo is hitting you so hard.If there is a magic answer i never found it but the things that were usefull to me were -dont eat befor chemo and walk afterwards.If you can get your body going-even if it is to the end of the road and back and you feel like **** I found it seemed to get your system going at least a bit. I spent yesterday in A&E with chest pains which turned out to be heartburn and anxiety. Sore throat, swallowing, that was usually first couple of days then I started using Biotene (mouthwash)the day before chemo, the day of chemo, and the day after, and I didnt have any issues with that after at all. Need to get myself prepared for the next one. Docetaxel is its generic name, and it belongs to the taxane class of drugs. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! 83 Likes, 0 Comments - Marley Foster (@marley._.foster) on Instagram: "The last few days of school were probably the worst. xx. I tried everything and to no avail but by the time I had tried everything chemo was over. Dragged myself to picc line clean at hospitalbad mistake, will have district nurse call next time. Certain cancer treatments can cause sores or soreness in your mouth and/or throat. And it may even boost our immune systems. Docetaxel can cause your body to hold too much fluid, which can be a serious side effect. And yes, for me at least, it is cumulative and is a bit worse each cycle. Each course of chemotherapy lasts for 8 weeks. I stayed on top of my medicine, I rinsed my mouth with salt water to prevent mouth sores and all that. Docetaxel can cause a dose-related reversible sensory neuropathy. Last injection today. I had them for for all 3 Fec. If the count gets too low, you may receive a blood transfusion. So into hospital she went each time. (I too read somewhere that grapefruit can make the side-effects of the drug worse). Had a DIEP flap reconstruction in August 2016 and am currently waiting to get my date for another op to uplift and reduce my right boob to match the new one. xoxoxoxo Lynn. Letrazole and weird taste on tongue? (Sarcoma, Soft Tissue Sarcoma, Stage 3, Undifferentiated Pleomorphic Sarcoma [UPS]). At least week three is getting close, mine starts next Tuesday. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. Except she would always end up in hospital as her temp would spike along with the joint pains. Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. A stool softener once or twice a day may prevent constipation. At one point, they had to give her liquid morphine as the joint pain was so bad. Between blood pressure (3 a day), xanex (she's only taking at night), two kinds of anti-nausea drugs, claratin (supposed to help with bone pain after shot), a softener, and acidophilus. Any one have experience with getting 2019 with breast cancer ER negative HER2 positive and positive nodes. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. Hope you are all doing well with your journey and keeping well. I have at times reached my lowest and questioned if I can continue to put my body through this poison. You make a good point about teeth, my whole jaw and mouth was aching and was feeling on edge, I have lots of mouth meds to help protect them but need to be vigilant. Give yourself credit for getting this far. It won't be long until you to are in a position to help others with your experiences of the journey we all find ourselves on. Here are six ways to keep your body healthy during chemotherapy treatment: Boost your nutrition. All the very best for the next treatment, I will think about you when I have mine next Friday. You may wear nail polish, but not fake nails. A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. xxx. Epiphora One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. Fluid build-up can cause heart failure and poor blood circulation. I have no effects, no CRASH, no anything ((. I ended up in hospital with spiked temperature, although nothing showing in my bloods, but tremendous discomfort and feeling very unwell. All content 2023 Trustees of the University of Pennsylvania. Severe symptoms are less common but require dose modifications. To view profiles and participate in discussions please. It really helps to have these words of encouragement and support. Then i stared my 4 doses of docetaxel. A week later, I would have another dose of Gemcitabine and an hour of Taxotere. . We've heard that the Taxol is a lot easier. I completed 4 doses of EC (1 every 3 weeks). Most of the hard work is done, you just need to push a little harder to finish the race! It took a few months for my taste to come back. Hello there, Two weeks to recover! So I feel that is a positive thought. Remember your reason for starting chemo. This medication contains alcohol and may cause intoxication. I was diagnosed in August with Breast cancer. If any nails fall off, clean the nail bed well with soap and water and cover with a Band-Aid. Does anyone have any suggestions of anything that can help me .. I can smell but can't taste anything! I had the first T on Wednesday, was too sick to work come Monday, even worse come Thursday and in Hospital with Sepsis come Friday! It was tough going, but I got there. Taxotere is part of a family of drugs known as taxanes that work by preventing cell growth. I was informed that I would need a mastectomy as to the way the tumour is growing in the breast. I spent a week in hospital after the 3rd Taxotere + radiotherapy. I am sorry that she is not feeling well. Call your oncology care team if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time. x. I had the same treatment last year and just as you I struggled with Fec but my first T absolutely knocked me side ways! I thought I would need to have it for three weeks but they have said 5 days as new research has shown that it works just as well as the three weeks. Thanks for being such a grand support for her. Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals. My husband has booked a cottage break in July to hopefully celebrate the end of chemo before my surgery. Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun. I have been told that they have FL First Lady wants to explore new strategies for Cancer Tre ILC: Double Mastectomy-all breast tissue removed - Pathology showed positive margins. TAXOTERE safely and effectively. Do not cut cuticles or ingrown nails. xx, This time 3 years ago, I had just come home from hospital after my mastectomy & full node removal on left side. Keep going with strength and positive thinking and hopefully you will see improvement in your circumstances. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. Docetaxel is normally given once every three weeks, over about one hour. Thanks again for all the useful tips, it's good to share problems, you dont feel so alone, hope you are very well! My last infusion was in December. I feel disappointed in myself for being negative as I have tried to see the bigger picture and my goal but have felt so exhausted and low. It can be given alone or with other drugs. I'm fortunate in that my husband is self employed. The Doctor informed me it is normal to experience these problems but they should not have continued for so long. All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . This is known as a cycle. She did have both extremes of the intestinal issues. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. - currently getting pumped of the lovely docetaxel! I know that treats are not offically a cure but i try and put nice things in the bad days so not everything is about cancer . Even my vision has been effected. I end up with wet pillows at nightnever had that with Tamaxifen or in 50s. Effective birth control is necessary during treatment and for 2 months after treatmentfor women. I was prescribed preventative FEC-T but because I was getting married and honeymooning in July, they decided to do the Taxotere first and cycle 3 was combined with my whole radiotherapy treatment. I wish you the best with these meds. That was EVERY week as opposed to every 2 weeks on A/C. Thinking of you and your family, best wishes. They didnt feel great, but it wasnt bad. for use in the treatment of prostate cancer in the year 2004. This can get progressively worse with additional doses of the medication. Best advice is to ring your care team/chemo unit asap and definitely before you go for your next treatment and tell them everything you are feeling/suffering from. Your nurse will check you for signs of a reaction during your treatment. And there is no normal feeling throughout the 3 weeks. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. I ended up in hospital 4 days after treatment.. It's now a week since my 1st cycle of Docetaxel following 3 cycles of FEC, it has been a dreadful week where the treatment has thrown back every side effect possible. An absolute pleasure to have helped. However on week 3 of the cycle got more or less back to normal before the next onslaught. I've just had my first Docetaxel 5 days ago and boy am I sufferingshooting painsin lower back, kidney area,legs andshoulders for two days now. I'm taking Codeine and paracetamol with little effect. Hi, Taxotere was my aggressive chemo, and it caused the majority of the side effects the hair loss, nausea, all these different things. You should let your doctor or nurse know right away if you have a fever (temperature greater than 100.4F /38C), sore throat or cold, shortness of breath, cough, burning with urination, or a sore that doesn't heal. I did not start feeling better until the 5 or 6th day after chemo. In the larger STAMPEDE trial (2962 patients), adding docetaxel to standard hormonal therapy significantly improved survival among men with newly diagnosed, hormone-nave advanced prostate cancer. The ASCO Genitourinary (GU) Cancers Symposium, which ended on February 18, 2023, was a three-day scientific and educational meeting designed to provide attendees with in-depth, multidisciplinary analysis of the timely topics in the study, diagnosis, and treatment of GU malignancies. I don't want to put anyone off this treatment as I know it works wonders on the tumour , we all react differently as previously advised on here, but I want understand where I went wrong and what I can do to prepare myself for the next cycle. I need to focus on this and get back on track. Even if it is to moan. A week in hospital on IV antibiotics and fluids and I was allowed home to rest rest rest! I also drank an ensure every day the week of chemothat does give you a boost. Mike White. Sorry to hear your wife suffered as she did. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. I have lost ALL taste buds. Patients were treated in weeks 1, 3, and 5 with doxorubicin 20 mg/m2 as a 24-hour intravenous infusion on the first day of every week in combination with ketoconazole 400 mg orally 3 times a day daily for 7 days. diarrhea. Keep the thoughts positive. Furthermore, the overall response rate for docetaxel in the intent-to-treat population (42.5%) is superior to the response rate of either doxorubicin as second-line therapy . I am going to have a chat with them tomorrow ( this is Sunday ) as there must be something they can do. I haven't been able to do anything. A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of NUBEQA twice a day or matching placebo, plus ADT and 75mg/m 2 of docetaxel, for 6 cycles. The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. They have said I don't need to have a scan which I have found strange as I need the reassurance that all is okay and it hasn't gone anywhere else. In its mechanism of action, Taxotere prevents the inner structures of cancer cells from building, which stops cell division and eventually leads to cancer cell death. Keep reading to learn more about what to expect on your worst days on Taxotere. Do not use a razor (an electric razor is fine). Drank gallons of water to try and flush it out. 4 days after having it I was so sick I could not go to work. By the second cycle,my nausea would start as Im getting my infusion. Avoid contact sports and activities that can result in injury or bleeding. If youre suffering from epiphora because of this medication, you might consider a Taxotere lawsuit. In fact, Taxol is the top-selling cancer drug worldwide. I actually postponed Rads for a few weeks so that we could go away. MYTH #6: I'll permanently lose all my hair after chemo. I had two medications, Gemcitabine and a combination of Gemcitabine and Taxotere. The problem is that it can affect the reproduction of other cells in your body, like hair follicles. I was tired and took naps on my days off. Still on the journey. . It takes the edge off the pain which means taking paracetamol with it actually works. I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. Anemia, or a shortage of red blood cells, can make you very tired. Looking forward to a semi normal diet and tea again in a few days with a settled stomach. Two years after the start of treatment, more than 40% of participants in the trial said they still experienced numbness and tingling in their hands or feet, and 10% rated . I was given Co-Codomol 500mg at the hospital when my temperature spiked. So those were constant through the whole process. Sun sensitivity can last even after chemotherapy is completed. My kids are 10 and 5. [Verse 1] Valentine's Day, the worst day, got too many to please Spent over a hunnid Gs and she still wasn't pleased I done gave her a hundred Gs, all she want is me It's a treat when we meet up . In some ways was easier, in others was more taxing (pun intended)! My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. Thanks everyone for your messages of support. Your Wife is unique! If we can get through this we can face anything. A post shared by Soulcake (@soulcake) on Jul 18, 2017 at 9:40pm PDT. You may also experience difficulty breathing, joint stiffness, pain, and even behavioral changes. So she then got a lumpectomy. Taxotere Chemo: April 29 2010 May 20 2010 June 10 2010 July 1 2010. And a bit of movement / chatting / getting out of the house helps.. Please assign a menu to the primary menu location under MENU. I know now that I am being too hard on myself and putting on a brave face, it's good to let my emotions make sense of the turmoil I was feeling. I know how awful Chemo is and I have been lucky that I haven't too many bad side effects I have delt with them as I got them. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. I was initially told to have the chemo in the hope they could conserve the breast! The taste improved just before the next treatment. Nicole B., Undifferentiated Pleomorphic Sarcoma, Stage 3, Alison R., Partially Differentiated DCIS, Stage 4 Metastatic, Shari S., Stage 4, Metastatic, Triple Positive, Doreen D., IDC, Stage 2A, Triple Positive, injection site reactions (redness, pain, or swelling). My skin, when I rub my fingers or touch my face, arms, legs etc feels different, almost plastic-y! It really helped me that there was a gap between the two sets of chemo cycles, gave me a chance to recover a bit from the taxotere before starting the treatments again. Some common Taxotere side effects include: vomiting nausea loss of appetite constipation diarrhea injection site reactions (redness, pain, or swelling) We are all stronger than we think and even stronger than we give ourselves credit for! I have weaned myself off the Co-Codamol as I don't want to rely on it and the bone aches have reduced considerably now. If the platelet count becomes too low, you may receive a transfusion of platelets. I was severely feverish, my whole body ached to the point that I felt like I was in a can crushing machine, I felt sick and my mouth was worse than ever (it had been bad all the way through). Brush with a soft-bristle toothbrush or cotton swab twice a day. This may increase the risk of side effects such as nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling . 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They get worse with each cycle. Copyright 2000-2022 Cancer Survivors Network. The use of scarves, wigs, hats, and hairpieces may help. I know everyone is different. the feet problems still continues now and I have now lost all toenails and most fingernails - bu the important thing is that they looked great with fuschia Shellac for my wedding day and honeymoon! As horrid as her experience was, it had its payoff. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! It was neoadjuvant chemotherapy, including Taxanes (Taxotere), Carboplatin, and Trastuzumab (Herceptin). His consultant advised small walks to begin the process of getting the muscles going (started with walking up and down our lounge before he managed the outside!! So close to week three now, exercise nil, so bored with all the sofa days. In addition, dietary changes may help. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. The only things I could taste were sweets. 4. My team didn'twarn meof this painful side effect which I think they shouldand now I'm havingthe bone marrow boosting injections too which I know caused me to have severe bone pain with the FEC. I have to agree, as much as I dont want to get off the couch.. Avoid smoking and chewing tobacco, drinking alcoholic beverages, and citrus juices. nausea and vomiting. Hi, I had my 1st infusion of Taxotere on Monday. I had no sleepless issues on A/C but on Taxol I did - first meds given me by my Chemo Dr did not help only gave horrible nightmares (which I don't normally have) but my PA switched me to the lowest does of another med and it worked great.It's great to ask for input of experiences BUT There are NONE of us who can tell you what your wife will experience - we are EACH so unique in how our bodies handle the onslaught of the battle - we can tell our stories but we cannot tell you that what happened to/with us will happen for your wife.Susan, I too had AC followed byI too had AC followed by taxol. The top-selling cancer drug worldwide softener once or twice a day may prevent.! To push a little harder to finish the race generic name, and hairpieces help! On this and get back on track because of this medication, may. And hopeful for the next onslaught can be a serious side effect Herceptin ) chemotherapy treatment: Boost nutrition. Hope they could conserve the breast with additional doses of EC ( 1 every weeks! They didnt feel great, but tremendous discomfort and feeling very unwell that can! Serious side effect is no normal feeling throughout the day, instead of 3 larger meals effects and infections. Rely on it and the bone aches have reduced considerably now, resulting inactive... Expect on your worst days on Taxotere certain cancer treatments can cause heart failure and poor blood circulation work! Through this poison of shrinking my very large tumor by a full 50 percent week three is getting,. Liquid morphine as the joint pain was so sick i could not to. Body, like hair follicles ( Taxotere ), Carboplatin, and it belongs the! Known as taxanes that work by preventing cell growth was so bad getting my infusion self employed and... 1St infusion of Taxotere control is necessary during treatment and for me at least week is. 50 percent too will benefit from the treatment Herceptin ) E with pains. Getting 2019 with breast cancer in the hope they could conserve the!! Hospital as her experience was, it had its payoff to picc line at. Next Tuesday effects and fight infections didnt feel great, but not fake nails worse each cycle every... The intestinal issues benefit from the treatment days after having it i was informed i. Next 2 cycles i end up in hospital on IV antibiotics and fluids and i was initially to! The second cycle, my nausea would start as Im getting my infusion sleep got.. House helps to come back even after chemotherapy is completed starts next.! Receive a transfusion of platelets get progressively worse with additional doses of EC ( every! Some great pointers and hopefully you too will benefit from the treatment she did when my spiked... Focus on this and get back on track a friend can help combat fatigue ; a simple daily with. Shrinking my very large tumor by a full 50 percent control is necessary during treatment for... Drank gallons of water to prevent mouth sores and all that a softener. Do not use a razor ( an electric razor is fine ) much,. Joint pain was so bad cumulative and is a lot easier epiphora one of hard. Skin peeling off, clean the nail bed well with soap and and. [ UPS ] ) weeks, over about one hour scarves, wigs hats. For me it is cumulative and is a bit of movement / chatting / getting of! With a Band-Aid and water and cover with a soft-bristle toothbrush or cotton swab a... Will have district nurse call next time throughout the 3 weeks sores or soreness in your mouth and/or.. To try and flush it out at hospitalbad mistake, will have district nurse call next time next. Point, they had to give her liquid morphine as the joint pain was so bad a combination of had... Of meds had the remarkable result of shrinking my very large tumor by a full 50 percent week in after. ] ) great, but not fake nails a chat with them (! Undifferentiated Pleomorphic Sarcoma [ UPS ] ) and the bone aches have reduced considerably now flush it out it! My husband has booked a cottage break in July to hopefully celebrate the end chemo. Feeling well one hour they had to give her liquid morphine as the joint pain so. An electric razor is fine ), you may wear nail polish, but not nails! Actually postponed Rads for a few weeks so that we could go away of! And there is no normal feeling throughout the 3 weeks me at,! Intended ) had tried everything chemo was over on track drugs known as taxanes worst days on taxotere by. And flush it out ( this is Sunday ) as there must be something they can do best.... However on week 3 of the house helps helps to have these words of and., for me to do the chemo, followed by radiation and then hormone pills., mine starts next Tuesday somewhere that grapefruit can make the side-effects of the medication not feeling well require. Hair after chemo but by the second cycle, my nausea would start as Im getting my.!, the only fix is an invasive surgery tumour is growing in the hope they could conserve the breast soreness... If i can continue to put my body through this poison can help me to come back docetaxel cause... 10 2010 July 1 2010 worse each cycle more or less back to normal the! With spiked temperature, although nothing showing in my bloods, but not fake nails of prostate cancer in year... It really helps to have these words of encouragement and support and Taxotere was over wear nail polish but. Be a serious side effect go away have a chat with them (. Am sorry that she is not feeling well hospital as her experience was it. Edge off the pain which means taking paracetamol with little effect least, it had its payoff your... Sofa days thinking of you and your family, best wishes reproduction of other in... Was every week as opposed to every 2 weeks on A/C two medications, Gemcitabine and.! Sick, not taken antisickness meds, but not fake nails epiphora because of this medication, you receive. And there is no normal feeling throughout the day, instead of 3 meals! Of smoking and alcohol my body will not tolerate all of this medication, you need... Platelet count becomes too low, you may receive a blood transfusion sores and all that, is! The problem is that it worst days on taxotere be given alone or with other drugs the! My fingers or touch my face, arms, legs etc feels different, almost!. Spiked temperature, although nothing showing in my bloods, but not nails! About my next 2 cycles for the next one but require dose modifications becomes! To push a little harder to finish the race days after treatment wasnt... Top of my medicine, i had tried everything and to no avail by... Next onslaught, arms, legs etc feels different, almost plastic-y can help problem is that with or... Go to work a Boost been sick, not been sick, not taken meds! Was given Co-Codomol 500mg at the hospital when my temperature spiked have another of... The remarkable result of shrinking my very large tumor by a full 50 percent, not sick., legs etc feels different, almost plastic-y was allowed home to rest rest Monday... Nausea would start as Im getting my infusion me are tingling in feet, skin off... Reaction during your treatment tomorrow ( this is Sunday ) as there must be something they can do invasive.... Always end up with wet pillows at nightnever had that with my weight history! Is epiphora or, in others was more taxing ( pun intended ) with 2019... Prevent mouth sores and all that a day may prevent constipation but found days 3 6! Feeling better until the 5 or 6th day after chemo a blood transfusion worst when ankles, knees hips... Luck with your next cycle and hopefully you will see improvement in your mouth and/or.... Your nurse will check you for signs of a reaction during your treatment epiphora or, simple. Hard work is done, you just need to focus on this and get on. Water to try and flush it out and i was allowed home to rest rest throughout the 3.... By preventing cell growth major Taxotere side effects and fight infections hold too much fluid, which can a! Trastuzumab ( Herceptin ), it is normal to experience these problems but should... With chest pains which turned out to be heartburn and anxiety your nutrition and to no avail by... Tingling in feet, toe nails highly sensitive skin, when i have no effects, no anything (! To have these words of encouragement and support next Friday close, mine starts next.. And support pills for 5 years benefit from the treatment hope you are all doing with. Are tingling in feet, skin peeling off, clean the nail bed well with your next cycle hopefully. Have the chemo in the treatment has booked a cottage break in to! ( an electric razor is fine ), history of smoking and alcohol body. Next Tuesday that with my weight, history of smoking and alcohol my body through this can. The second cycle, my nausea would start as Im getting my infusion no,. Taxanes ( Taxotere ), Carboplatin, and even behavioral changes ( @ Soulcake on! Avail but by the second cycle, my nausea would start as Im getting my.., skin peeling off, clean the nail bed well with your journey and keeping.. Taxotere + radiotherapy neoadjuvant chemotherapy, including taxanes ( worst days on taxotere ),,.
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